Has anyone ever had nerve damage as a result of a picc line being inserted or as a result of chemotherapy?

My wife had a picc line inserted 8 weeks ago which wouldnt go in properly and caused severe nerve pain.Then chemo was given with a half line and seemed to leak so the line was removed and a central line put in a week later to continue giving chemo.But 24 hrs after the failed picc line insertion she started having severe pain in her right arm and now its still very painful and she has lost the use of her arm.Docs say they have never seen this happen before and it may mean permanent loss of use.